Basic fibroblast growth factor may improve devascularized sternal healing
نویسندگان
چکیده
منابع مشابه
Gelatin sheet incorporating basic fibroblast growth factor enhances healing of devascularized sternum in diabetic rats.
BACKGROUND Poor healing of the sternum often limits the use of bilateral internal thoracic arteries (BITAs) after coronary bypass surgery in diabetic patients. We have reported that a gelatin sheet that incorporates basic fibroblast growth factor (bFGF) accelerates sternal healing after BITA removal in normal rats. This study evaluated the effects of the above method for sternal healing in diab...
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BACKGROUND Tendon injuries are common and it takes a long time for an injured tendon to heal. Adverse phenomena such as adhesion and rupture are associated with these injuries. Finding a method to reduce the time required for healing whichimproves the final outcome, will lead to decreased frequency and intensity of adverse consequences. This study was designed to investigate the effects ...
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BACKGROUND Poor healing of the sternum often limits the use of bilateral internal thoracic arteries (BITAs) in coronary bypass surgery, especially for diabetic patients. We have reported that basic fibroblast growth factor (bFGF) enhanced regeneration of the skull. This study was designed to evaluate the effects of topical use of bFGF on sternal healing after removing the BITAs. METHODS AND R...
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The stimulatory effect of recombinant basic fibroblast growth factor (bFGF) on wound healing was assessed using healing-impaired (db/db) mice. Full-thickness wounds were made in female diabetic C57BL/KsJ db/db mice, and their normal (db/+) littermates with a punch biopsy instrument. Recombinant bFGF was applied locally to the open wound once a day. The mice were later killed and histological se...
متن کاملRecombinant Basic Fibroblast Growth Factor Stimulates Wound Healing in Healing-impaired dbldb Mice
The stimulatory effect of recombinant basic fibroblast growth factor (bFGF) on wound healing was assessed using healing-impaired (db/db) mice. Full-thickness wounds were made in female diabetic C57BL/Ksj AM mice, and their normal (db/+) littermates with a punch biopsy instrument . Recombinant bFGF was applied locally to the open wound once a day. The mice were later killed and histological sect...
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ژورنال
عنوان ژورنال: The Annals of Thoracic Surgery
سال: 2000
ISSN: 0003-4975
DOI: 10.1016/s0003-4975(00)01645-3